SELECTIVE ALKYLATION OF KETONES WITH A BULKY ALUMINUM REAGENT - THE THF-TBSOTF SYSTEM

Authors
SAITO S ITO M MARUOKA K YAMAMOTO H
Citation
S. Saito et al., SELECTIVE ALKYLATION OF KETONES WITH A BULKY ALUMINUM REAGENT - THE THF-TBSOTF SYSTEM, Synlett, (4), 1997, pp. 357
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
4
Year of publication
1997
Database
ISI
SICI code
0936-5214(1997):4<357:SAOKWA>2.0.ZU;2-Z
Abstract
Various ketones can be alkylated with tetrahydrofuran (THF) to provide alpha-siloxybutylated ketones in the presence of a bulky aluminum rea gent, lithium diisopropylamide (LDA), and t-butyldimethylsilyl triflat e (TBSOTf).