QUICK RESPONSE OF ADVANCED CANCER TO CHEMORADIATION THERAPY WITH ANTINEOPLASTONS

Antineoplastons A10 and AS2-1 exhibit growth inhibition of cancer cell s by diverse modes of action. We observed antitumor responses within 2 -3 weeks of a combination treatment of chemoradiation therapy and anti neoplastons A10 and AS2-1 in phase I clinical study being conducted in Kurume University Hospital. We reviewed 3 clinical cases of advanced cancer (multiple metastatic lung cancer, thalamic glioma and primary l ung cancer) in which we believed antineoplaston A10 and AS2-1 may be c ontributing to the rapid antitumor response. The possible use of this combination for induction therapy in advanced cancer is discussed.