STUDIES ON HYPERTHERMIA COMBINED WITH ARTERIAL THERAPEUTIC BLOCKADE FOR TREATMENT OF TUMORS - (PART-III) EFFECTIVENESS OF HYPERTHERMIA COMBINED WITH ARTERIAL CHEMOEMBOLIZATION USING DEGRADABLE STARCH MICROSPHERES ON ADVANCED LIVER-CANCER

Authors
MURATA T AKAGI K IMAMURA M NASU R KIMURA H NAGATA K TANAKA Y
Citation
T. Murata et al., STUDIES ON HYPERTHERMIA COMBINED WITH ARTERIAL THERAPEUTIC BLOCKADE FOR TREATMENT OF TUMORS - (PART-III) EFFECTIVENESS OF HYPERTHERMIA COMBINED WITH ARTERIAL CHEMOEMBOLIZATION USING DEGRADABLE STARCH MICROSPHERES ON ADVANCED LIVER-CANCER, Oncology Reports, 5(3), 1998, pp. 709-712
Citations number
19
Categorie Soggetti
Oncology
Journal title
Oncology Reports → ACNP
ISSN journal
1021335X
Volume
5
Issue
3
Year of publication
1998
Pages
709 - 712
Database
ISI
SICI code
1021-335X(1998)5:3<709:SOHCWA>2.0.ZU;2-P
Abstract
Arterial chemoembolization using degradable starch microspheres and ad riamycin was combined with hyperthermia to treat advanced liver cancer . The prolonged peak adriamycin level in hepatic venous blood suggeste d that the drug persisted for longer in the liver after injection cont aining microspheres. Heating efficiency was increased more in tumor ti ssue than in normal liver tissue after embolization. This combined the rapy was performed in eight patients with advanced liver cancer and wa s effective in three (complete or partial remission). The mean surviva l time was 25 weeks and there were no severe side effects. This combin ed therapy may be useful for liver cancer.