MAPPING THE COMMON ANTIGENIC DETERMINANTS IN AVIDIN AND STREPTAVIDIN

Authors
SUBRAMANIAN N ADIGA PR
Citation
N. Subramanian et Pr. Adiga, MAPPING THE COMMON ANTIGENIC DETERMINANTS IN AVIDIN AND STREPTAVIDIN, Biochemistry and molecular biology international, 43(2), 1997, pp. 375-382
Citations number
13
Journal title
Biochemistry and molecular biology international → ACNP
ISSN journal
10399712
Volume
43
Issue
2
Year of publication
1997
Pages
375 - 382
Database
ISI
SICI code
1039-9712(1997)43:2<375:MTCADI>2.0.ZU;2-6
Abstract
An epitope scan analysis of the whole sequence of avidin and core stre ptavidin using polyclonal antibodies to these two antigens reveal the presence of multiple common epitopes in both the proteins. These antig enic determinants consist mostly of either identical or similar residu es. The antibody recognition sites in both antigens are shown to be lo calized to homologous regions.