RHOMBENONE - FARNESYL-PROTEIN TRANSFERASE INHIBITOR FROM THE LEAVES OF HEDERA-RHOMBEA BEAN

Authors
KWON BM LEE SH KIM KS LEE LR LEE UC HONG SH BOK SH
Citation
Bm. Kwon et al., RHOMBENONE - FARNESYL-PROTEIN TRANSFERASE INHIBITOR FROM THE LEAVES OF HEDERA-RHOMBEA BEAN, Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 971-974
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
8
Year of publication
1997
Pages
971 - 974
Database
ISI
SICI code
0960-894X(1997)7:8<971:R-FTIF>2.0.ZU;2-S
Abstract
Rhombenone, a new dammarane analogue containing an 25-oxo, which inhib its farnesyl protein transferase (FPTase), was isolated from the leave s of Hedera rhombea Bean. Additional related dammaranes were also eval uated for FPTase inhibition. (C) 1997 Elsevier Science Ltd.