Severe hypophosphatemia has rarely been reported as a cause of acute p
aralysis. We present the clinical and electrophysiological findings on
a patient who developed quadriparesis following several surgeries for
complicated cholecystectomy. The paralysis was most likely the result
of severe hypophosphatemia causing a neuropathy which improved readil
y after proper phosphate replacement. The possible pathogenic mechanis
ms of hypophosphatemic neuropathy are discussed. (C) 1998 John Wiley &
Sons, Inc.