SYNTHESIS AND ESTROGEN-RECEPTOR BINDING AFFINITIES OF THE MAJOR HUMANMETABOLITES OF RALOXIFENE (LY139481)

Authors
DODGE JA LUGAR CW CHO S OSBORNE JJ PHILLIPS DL GLASEBROOK AL FROLIK CA
Citation
Ja. Dodge et al., SYNTHESIS AND ESTROGEN-RECEPTOR BINDING AFFINITIES OF THE MAJOR HUMANMETABOLITES OF RALOXIFENE (LY139481), Bioorganic & medicinal chemistry letters, 7(8), 1997, pp. 993-996
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Medicinal
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
8
Year of publication
1997
Pages
993 - 996
Database
ISI
SICI code
0960-894X(1997)7:8<993:SAEBAO>2.0.ZU;2-M
Abstract
Glucuronide conjugates 1 and 2, the major metabolites of raloxifene, h ave been prepared and their molecular interactions with the estrogen r eceptor determined. (C) 1997 Elsevier Science Ltd.