Sera collected from European wild boar (Sus scrofa) shot in Eastern Ge
rmany between January 1991 and December 1994 were tested for antibodie
s to pseudorabies virus (PRV). Of 3,143 sera tested, 281 (8.9%) and 13
(0.4%) were positive and suspect in an enzyme-linked immunosorbent as
say (ELISA), respectively. The specificity of the reactions was confir
med by detection of neutralizing antibodies in 220 sera (74.8%) and by
immunoblotting. Analysis of host age and sex of the animals, temporal
and spatial factors showed significantly higher seroprevalences in ol
der animals than in younger individuals, but no differences between ma
les and females. Pseudorabies virus infections have been endemic in th
is wild boar population for several years and the extreme eastern part
of the study area had significantly higher seroprevalences (less than
or equal to 22%) than other areas. In the area covered by this study,
pseudorabies virus was eradicated in the domestic animal populations
in 1985. Thus, the infections in the wild boar population appear to be
endemic and persist completely separately and without affecting the d
omestic pig population.