SYSTEMIC COMPLEMENT ACTIVATION IN PSORIASIS-VULGARIS

Authors
FLEMING CJ HOLME ER MACKIE RM
Citation
Cj. Fleming et al., SYSTEMIC COMPLEMENT ACTIVATION IN PSORIASIS-VULGARIS, Clinical and experimental dermatology, 21(6), 1996, pp. 415-418
Citations number
17
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Clinical and experimental dermatology → ACNP
ISSN journal
03076938
Volume
21
Issue
6
Year of publication
1996
Pages
415 - 418
Database
ISI
SICI code
0307-6938(1996)21:6<415:SCAIP>2.0.ZU;2-9
Abstract
Nineteen patients with psoriasis vulgaris and no other cause for syste mic complement activation were studied for evidence of such activation . There was a marked elevation in serum C5b-9 complexes with no other significant complement abnormalities, and no correlation between C5b-9 levels and disease activity. This is the most detailed study of compl ement in psoriasis yet attempted and confirms that complement activati on is a feature of psoriasis vulgaris.