Aim. To assess the prevalence of DSM-III-R axes I and II disorders and
the severity of psychiatric symptoms in cannabis users who did not us
e other illicit drugs. Design. Cross-sectional psychiatric examination
of subjects with different patterns of cannabis use: cannabis depende
nce, abuse and occasional use. Participants. One hundred and thirty-th
ree cannabis users identified through random urine testing of draftees
to the Italian army and interviewed after 2-5 days of abstinence from
drug use. Measurements. The subjects completed the Beck Depression In
ventory, the Spielberger State-Trait Anxiety Index and the 20-item rev
ised Toronto Alexithymia Scale and were then interviewed with the Stru
ctured Clinical Interview for DSM-III-R. Findings. The prevalence of c
o-morbid psychiatric disorders varied with the pattern of cannabis use
: 83% of subjects with DSM-III-R cannabis dependence, 46% of those wit
h DSM-III-R cannabis abuse and 29% of occasional users received at lea
st one DSM-III-R psychiatric diagnosis. The severity of depressive, an
xious and alexithymic symptoms increased progressively with the degree
of involvement with cannabis. Conclusions. In this sample of young me
n the risk of associated psychiatric disabilities varied with the patt
ern of cannabis use. Chronic use of cannabis was associated with a hig
h prevalence of co-morbid psychiatric disorders.