GEOMETRICALLY DIRECTED SELECTIVE STEROID HYDROXYLATION WITH HIGH TURNOVER BY A FLUORINATED ARTIFICIAL CYTOCHROME-P-450

Authors
BRESLOW R GABRIELE B YANG J
Citation
R. Breslow et al., GEOMETRICALLY DIRECTED SELECTIVE STEROID HYDROXYLATION WITH HIGH TURNOVER BY A FLUORINATED ARTIFICIAL CYTOCHROME-P-450, Tetrahedron letters, 39(19), 1998, pp. 2887-2890
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
19
Year of publication
1998
Pages
2887 - 2890
Database
ISI
SICI code
0040-4039(1998)39:19<2887:GDSSHW>2.0.ZU;2-4
Abstract
A metalloporphyrin has been synthesized carrying a beta-cyclodextrin g roup on tetrafluorophenyl rings at the four meso positions of the porp hyrin. It performs the selective hydroxylation of an androstanediol de rivative with complete positional selectivity and 187 turnovers. (C) 1 998 Elsevier Science Ltd. All rights reserved.