MAMMALIAN CRANIOFACIAL EMBRYOLOGY IN-VITRO

Our review demonstrates that the whole embryo culture system establish ed by New and his colleagues, in combination with beneficial fluoresce nt dye cell-tracing techniques, has greatly contributed to many advanc ements in the field of mammalian craniofacial embryology, especially w ith regard to elucidating the developmental behavior of cephalic crest cells. In addition, based on recent results, further combining whole embryo culture with mandibular organ culture methods has allowed us to trace cranial crest cells for a much longer developmental period, i.e ., presently up to the cap stage in odontogenesis.