High reliability systems generally require individual system component
s having extremely high reliability over long periods of time. Short p
roduct development times require reliability tests to be conducted wit
h severe time constraints. Frequently few or no failures occur during
such tests, even with acceleration. Thus, it is difficult to assess re
liability with traditional life tests that record only failure times.
For some components, degradation measures can be taken over time. A re
lationship between component failure and amount of degradation makes i
t possible to use degradation models and data to make inferences and p
redictions about a failure-time distribution. This article describes d
egradation reliability models that correspond to physical-failure mech
anisms. We explain the connection between degradation reliability mode
ls and failure-time reliability models. Acceleration is modeled by hav
ing an acceleration model that describes the effect that temperature (
or another accelerating variable) has on the rate of a failure-causing
chemical reaction. Approximate maximum likelihood estimation is used
to estimate model parameters from the underlying mixed-effects nonline
ar regression model. Simulation-based methods are used to compute conf
idence intervals for quantities of interest (e.g., failure probabiliti
es). Finally we use a numerical example to compare the results of acce
lerated degradation analysis and traditional accelerated life-test fai
lure-time analysis.