The authors report four patient cases of delirium in which medications
were used to restore mental capacity when life-or-death treatment dec
isions were required. Although extensive literature on substituted jud
gment exists for delirium and depression compromising capacity to make
competent decisions, the authors could locate to articles proposing a
ggressive delirium treatment for restoring patients' capacity to parti
cipate in their own care. Without surgical intervention, all four of t
he authors' patients faced imminent death. Without psychopharmacologic
banishment of the patients' deliria, proxies would have been asked wh
ether the patients should undergo potentially lifesaving but high-risk
procedures. The patients would have lost the opportunity to express t
heir wishes about heroic lifesaving medical measures.