INTRACRANIAL PLASMA-CELL GRANULOMA AND HOMOCYSTINURIA

A rare case of plasma cell granuloma (PCG) of the brain is reported. A n 18-year-old man with a well known homocystinuria and a history of se vere oligophrenia, grand-mal-epilepsia, bilateral ectopia lentis requi ring extraction of both lens and operatively corrected genu valgum, di ed suddenly within a few minutes. In 1993 a hypergammaglobulinemia was noticed and a decortication on the left side after purulent pneumonia became necessary. Four months before death, multiple abscesses in the spleen and pancreas led to splenectomy and resection of the pancreati c tail. Autopsy revealed a pulmonary embolism and an isolated intracra nial plasma cell granuloma of the left hemisphere.