The imaging of crystal defects by high-resolution transmission electro
n microscopy or with the help of the electron diffraction contrast tec
hnique is well known and routinely used. However, a direct and phenome
nological analysis of electron micrographs is mostly not possible, but
requires the application of image simulation and matching techniques,
The trial-and-error matching technique is the indirect solution to th
e direct scattering problem applied to analyse the nature of the objec
t under investigation. Alternatively, inverse problems as direct solut
ions of electron scattering equations can be deduced using either an i
nvertible linearized eigenvalue system or a discretized form of the di
ffraction equations. This analysis is based on the knowledge of the co
mplex electron wave at the exit plane of an object reconstructed for t
he surrounding of single reflections by electron holography or other w
ave reconstruction techniques. in principle, it enables directly the r
etrieval of the local thickness and orientation of a sample as well as
the refinement of potential coefficients or the determination of the
atomic displacements, caused by a crystal lattice defect, relative to
the atom positions of the perfect lattice. Considering especially the
sample orientation as perturbation the solution is given by a generali
zed and regularized Moore-Penrose inverse, where the resulting numeric
al algorithms imply ill-posed inverse problems.