Plasma lipids represent a major determinant for the development of cor
onary heart disease (CHD) and thus mortality in the industrialised wor
ld. Drug therapies that alter lipid levels have continued to demonstra
te a mortality benefit in certain types of dyslipidaemia. Many enterpr
ises are pursuing further agents that reduce the risk of CHD-events by
established as well as novel mechanisms. This review provides a summa
ry of the patents filed for such endeavours over the preceding two yea
rs.