We report a right atrial myxoma which suddenly developed in a thalasse
mic patient after allogeneic bone marrow transplantation. The tumor wa
s first detected by echocardiography on day +47 after transplant and t
he patient underwent surgical removal of the myxoma on day +103, The p
ost-operative course was uneventful, and at more than 3 years from the
event, he is alive and well, cured from his congenital disease, with
no detectable intra-cardiac tumor. The onset of the myxoma in the earl
y post-transplant period and the extremely high velocity of growth sug
gest a possible relationship of this condition with the immunosuppress
ive status.