A rare case of mucinous adenocarcinoma presented as a solitary, metast
atic deposit to a region of Paget's disease within the peripheral skel
eton. Historical, physical, radiographic, and scintigraphic findings w
ere indistinguishable from those of sarcomatous degeneration arising f
rom pagetoid bone, This case supports the idea that when a painful, os
teolytic lesion is discovered within a region of Paget's disease, bone
scintigraphy has greater value for disclosing potential multifocal or
multicentric disease than for providing etiologic specificity for the
principal lesion.