IMPROVEMENT OF FECAL CONTINENCE THROUGH S TIMULATION OF THE M-SPHINCTER ANI EXTERNUS

Using the pig as a model, it was shown that stimulation of the distal nerve ending of the pudendal nerve leads to the isolated stimulation o f the external anal sphincter muscle. No difference in pressure respon se was noted after application of between 0.5 and 1.5 mA unilateral or bilateral stimulation. Major advantages observed using between 1.5 an d 3.5 mA bilateral stimulation; with a stimulation between 2.0 and 2.5 mA the pressure response was twice as high compared to unilateral sti mulation. Continuous stimulation of the striated anal sphincter muscle leads to fatigue, reaching 50% fatigue after a median time between 40 -90 s. In cyclic stimulation (alternation every 15 s, duration 20 min) a fatigue reaction was also seen. The peak pressure decreased after 2 0 min for a median of 11%, the final pressure was lowered in 15% follo wing a logarithmic curve pattern. The experimental application of vari able impulse ranges also caused pressure differences. Increasing the i mpulse range from 200 to 450 mu s (peak pressure) vs. 400 mu s (final pressure) resulted in a statistically significant pressure increase. T herefore, it was proven that selective stimulation of the external ana l sphincter muscle can lead to a transient pressure increase, which po ssibly improves fecal continence.