METANEPHRIC ADENOMA OF THE KIDNEY - A CLI NICOPATHOLOGICAL, IMMUNOHISTOCHEMICAL AND ELECTRON-MICROSCOPIC STUDY OF 2 CASES

We report two cases of metanephric adenoma in 40 and 48 year-old women . These rare kidney tumors were composed of cuboidal epithelial cells forming tubules, glomeruloid structures and sheets. Ultrastructural an d immunohistochemical studies revealed that the tumor cells are simila r to epithelial cells of developing nephrons. These features different iate the metanephric adenoma from tubulo-papillary renal carcinoma, ne phroblastoma, and cortical adenoma. According to its invariably benign course, the metanephric adenoma treatment could be restricted to a si mple tumorectomy.