PERFORATION OF TERMINAL ILEUM AND APPENDIX IN TYPHOID ENTERITIS - REPORT OF 2 CASES

Two cases of simultaneous typhoid perforation of terminal ileum and ap pendix are reported from Harare Central Hospital, These findings have not been reported before. Perforations were associated with schistosom iasis and HIV/AIDS, Definitive diagnosis was made only after laparotom y, serology and histopathology. With early diagnosis, effective resusc itation and timely intervention, this life-threatening condition is no t necessarily fatal. Septic shock is however, an ominous sign of poor prognosis, In the tropics, bradycardia, leukopaenia and perforation in a febrile patient with right iliac fossa tenderness should arouse sus picion. Perforations may occur in patients with underlying diseases.