Study objective: To determine whether condensation on the inner surfac
e of the endotracheal tube (vapor trail) is a reliable indicator of in
tratracheal placement. Methods: Twenty-seven separate experiments were
conducted on 10 conditioned, mongrel dogs weighing 15 to 20 kg each.
After induction of anesthesia, an endotracheal tube was placed in the
trachea under direct visualization. A second, identical endotracheal t
ube was then placed in the esophagus. An attending emergency physician
, blinded to tube placement, then used a bag-valve apparatus to manual
ly ventilate each endotracheal tube in turn. Five ventilations were pe
rformed on each tube, and the presence or absence of condensation on t
he inner surface of the tube was recorded. A second physician, blinded
both to tube placement and to the actions of the first assessor, then
repeated the ventilation and assessment of both tubes. Results: Vapor
trail was observed in 27 (100%) of 27 endotracheal tubes correctly pl
aced in the trachea (95% confidence interval [CI], 90% to 100%) and in
23 (83%) of 27 tubes placed in the esophagus (95% CI, 66% to 96%). Ph
ysicians concurred in all cases. Absence of vapor trail was 15% sensit
ive (95% CI, 4% to 34%) for indicating incorrect (esophageal) tube pla
cement. Conclusion: In this model, condensation on the inner surface o
f the endotracheal tube was common after placement within the esophagu
s. If these results are confirmed in human studies, the presence of a
vapor trail should not be used as a clinical indicator of correct endo
tracheal tube placement.