Objectives. To review studies in the scientific literature of five phy
sical interventions commonly recommended for children with neurodevelo
pmental delay. Design. A literature search for and a review of the res
ults of controlled and other studies conducted in the course of the la
st 25 years. Setting. institute of Child Health, University of Cape To
wn. Subjects. Patterning; neurodevelopmental therapy; sensory integrat
ive therapy; optometric visual training; auditory integration therapy.
Outcome measures. Findings and conclusions drawn in the studies revie
wed. Results. Controlled studies fail to provide evidence to support c
laims made for the five interventions examined. Conclusions. In the ab
sence of scientific evidence for efficacy patterning, neurodevelopment
al therapy, sensory integrative therapy optometric visual training and
auditory integrative therapy cannot be recommended far children with
neurodevelopmental delay.