Ca. Owens et al., THE INACCURACY OF DUPLEX ULTRASONOGRAPHY IN PREDICTING PATENCY OF TRANSJUGULAR INTRAHEPATIC PORTOSYSTEMIC SHUNTS, Gastroenterology, 114(5), 1998, pp. 975-980
Background & Aims: A prospective double-blinded study with preset sono
graphic criteria has not been performed to assess the accuracy of dupl
ex ultrasonography in determining the patency of transjugular intrahep
atic portosystemic shunts (TIPS). The purpose of this study was to det
ermine the sensitivity and specificity of duplex ultrasonography in pr
edicting shunt malfunction using accepted preset sonographic criteria.
Methods: Sixty ultrasonographic and venographic follow-up comparisons
were made on 38 cirrhotic patients who had undergone TIPS placement f
or variceal bleeding (n = 28) or intractable ascites (n = 10). Ultraso
nographic results were analyzed by one of two board-certified ultrason
ographers without knowledge of venographic findings. Results: Of the 3
1 occluded (n = 8) and stenotic (n = 23) shunts, ultrasonography accur
ately predicted a shunt malfunction (occlusion or stenosis) in only 11
studies and incorrectly predicted patency in 20. Compared with venogr
aphy, ultrasonography had a sensitivity of 35% and a specificity of 83
% in predicting TIPS stenosis or occlusion. Conclusions: These results
suggest that duplex sonography is not a sensitive test in predicting
the presence of a hemodynamically significant stenosis and that shunt
status should be assessed by venography and direct portal pressure mea
surements until a more reliable and proven noninvasive ultrasonographi
c criterion is devised.