N. Bernard et al., PERSONAL EXPOSURE TO NITROGEN-DIOXIDE POLLUTION AND EFFECT ON PLASMA ANTIOXIDANTS, Archives of environmental health, 53(2), 1998, pp. 122-128
We conducted a cross-sectional epidemiological study to evaluate perso
nal exposure to nitrogen dioxide and its effect on blood antioxidants.
Personal exposure of 107 volunteers was assessed for 14 d with passiv
e monitors. We excluded heavy smokers (> 10 cigarettes/d) from time st
udy, Sociodemographic and environmental data, as well as beta-carotene
intake, were recorded, We mainly attributed the mean nitrogen dioxide
personal exposure (31.9 +/- 12.7 mu g/m(3) [0.017 ppm or 0.70 mu M.m(
3)]) (R-2 = 0.75) to residence site in the city, time spent in urban t
raffic, and use of gas stoves. The correlation between nitrogen dioxid
e exposure and blood antioxidant concentration was weak; in addition,
the correlation coefficients for men and women were inconsistent. None
theless, we found some evidence of an interaction between carotene int
ake and nitrogen dioxide exposure: a significantly lower plasma beta-c
arotene level was evident among subjects who consumed less than or equ
al to 4.5 mg/jour of carotene and who were exposed to nitrogen dioxide
levels that exceeded 40 mu g/m(3) (0.021 ppm or 0.87 mu M/m(3)) of ni
trogen dioxide.