Neuropsychiatric disorders make up a large proportion of medical condi
tions causing disability and death worldwide. This paper reviews the m
ost significant neurological disorders, emphasizing the preventability
of most of them. The worldwide impact of cerebrovascular disease, pro
tein-energy malnutrition causing cognitive impairment, tetanus, dement
ia, meningitis, and epilepsy is summarized. The burden of neurological
dysfunction as a complication of tuberculosis, measles, road accident
s, congenital anomalies, malaria, falls, war, violence, alcohol, HIV,
diabetes, syphilis, and rheumatic heart disease might also be lessened
by preventive measures. As in other health problems, major risk facto
rs are poverty, poor access to health care, and social instability.