Cj. Phillips, THE ECONOMIC-IMPLICATIONS OF IMPLEMENTING EVIDENCE-BASED DIABETIC TREATMENT STRATEGIES, International journal of clinical practice, 52(3), 1998, pp. 181-187
In Type I diabetes, conclusive evidence exists that intensive insulin
strategies can achieve normal or near normal blood glucose levels and,
as a result, reduce the risk of major complications and produce major
benefits in years of life, years of sight, and years free from end-st
age renal disease and amputation. The evidence in Type II diabetes is
less clear but claims are made that insulin-based strategies should be
started earlier, even at initial diagnosis. Intensive strategies have
also been shown to improve survival in diabetic patients with acute m
yocardial infarction. The economic implications of introducing intensi
ve insulin-based strategies have assumed different rates of obesity an
d patients currently receiving insulin. Since the costs of an intensiv
e insulin-based strategy are approximately 50% more than conventional
strategies, the average cost per diabetic patient will increase by hal
f the percentage increase in patients receiving intensive therapy. It
is argued that the extra costs incurred by the switch in therapy are l
ikely to be offset by savings made as a result of reductions in expens
ive episodes of care, such as hospitalisation. In addition, evidence e
xists to show that such a switch is cost effective in generating addit
ional life years and quality adjusted life years for diabetics.