INVOLVEMENT OF NITRIC-OXIDE SYNTHASE IN PROTEINURIA ASSOCIATED WITH CHRONIC RENAL-DISEASE IN RATS

Authors
BROOKS DP CONTINO LC
Citation
Dp. Brooks et Lc. Contino, INVOLVEMENT OF NITRIC-OXIDE SYNTHASE IN PROTEINURIA ASSOCIATED WITH CHRONIC RENAL-DISEASE IN RATS, Pharmacology, 56(5), 1998, pp. 257-261
Citations number
15
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
Pharmacology → ACNP
ISSN journal
00317012
Volume
56
Issue
5
Year of publication
1998
Pages
257 - 261
Database
ISI
SICI code
0031-7012(1998)56:5<257:IONSIP>2.0.ZU;2-2
Abstract
The present study demonstrates that the nitric oxide synthase inhibito r, aminoguanidine, can attenuate the proteinuria observed in a predomi nantly noninflammatory model of chronic renal disease in the rat. Thes e data suggest that nitric oxide synthase may be involved in progressi ve renal disease.