PERIPHERAL PRIMITIVE NEUROECTODERMAL TUMOR PRESENTING WITH DIFFUSE CUTANEOUS INVOLVEMENT AND 7-22 TRANSLOCATION

Authors
SMITH LM ADAMS RH BROTHMAN AR VANDERHOOFT SL COFFIN CM
Citation
Lm. Smith et al., PERIPHERAL PRIMITIVE NEUROECTODERMAL TUMOR PRESENTING WITH DIFFUSE CUTANEOUS INVOLVEMENT AND 7-22 TRANSLOCATION, Medical and pediatric oncology, 30(6), 1998, pp. 357-363
Citations number
16
Categorie Soggetti
Oncology,Pediatrics
Journal title
Medical and pediatric oncology → ACNP
ISSN journal
00981532
Volume
30
Issue
6
Year of publication
1998
Pages
357 - 363
Database
ISI
SICI code
0098-1532(1998)30:6<357:PPNTPW>2.0.ZU;2-P
Abstract
We report an unusual case of peripheral primitive neuroectodermal tumo r (pPNET) in an infant presenting with congenital cutaneous nodules an d a t(7;22)(p21;q11.2). The biologic behavior of the tumor diverged ov er time from a slowly growing tumor with multiple cutaneous nodules to a more aggressive neoplasm characterized by pulmonary metastases and a soft tissue mass showing additional cytogenetic alterations. (C) 199 8 Wiley-Liss, Inc.