Uo. Wenzel et al., DIAGNOSTIC AND THERAPEUTIC MEASURES TAKEN BY DOCTORS ON PATIENTS IN AHYPERTENSIVE CRISIS - AN INQUIRY OF 56 MEDICAL-CENTERS, Deutsche Medizinische Wochenschrift, 123(15), 1998, pp. 443-447
Background and objective: Despite official guidelines on the diagnosis
and treatment of hypertensive crisis, the extent to which they are be
ing followed in routine medical practice is unknown. This study was un
dertaken to discover how hospital doctors were handling cases of hyper
tensive crisis (HC). Material and methods: Physicians were requested t
o participate in a multiple-choice questionnaire study, relating to th
e diagnosis of HC, any emergency diagnosis and choice of antihypertens
ive drugs, these questionnaires to be distributed among the medical st
aff. Ultimately 463 questionnaires tone per doctor) were sent out and
325 were completed (response rate of 70%). Results: The most frequentl
y mentioned blood pressure values characteristic for HC were > 200 sys
tolic and > 120 diastolic. 160/90 was given most often as the therapeu
tic goal, which most doctors wanted to reach ire an HC within 30 to 60
min. The calcium-antagonist nifedipin was the drug of first choice fo
r almost all clinical presentations. Second was intravenously urapidil
, an alpha-agonist. Nitroglycerin was named as first choice only for p
ulmonary oedema or myocardial infarction. In everyone of the stated co
nditions most doctors were eager to avoid using beta-blockers. As for
the drug of first choice in associated myocardial infarction, 111 doct
ors named nifedipin, 28 wanted to avoid it and 45 considered it contra
indicated. Conclusion: These data show a marked discrepancy between re
commended guidelines and actual practice in the management of hyperten
sive crisis.