BRUCELLA ENDOCARDITIS OF THE AORTIC-VALVE

Brucella endocarditis was diagnosed in two patients with acute renal f ailure. Both patients had major aortic insufficiency, congestive cardi ac failure and clinical and laboratory signs of an active infection, a lthough adequate antibacterial therapy had already been introduced. Re placement of the aortic valve, together with the aortic root in one of the cases, were carried out as emergency procedures, followed by anti bacterial treatment with rifampicin, doxycycline and co-trimoxazole. B oth patients left the hospital cured and are well 2.5 and 2 years afte r the surgery, respectively. (C) 1998 Elsevier Science B.V.