MUKAIYAMA-TYPE, 8-MEMBERED RING-CLOSURE - ACCESS TO A TRICYCLIC SYSTEM RELATED TO TAXANES

Authors
CAVE C VALANCOGNE I CASAS R DANGELO J
Citation
C. Cave et al., MUKAIYAMA-TYPE, 8-MEMBERED RING-CLOSURE - ACCESS TO A TRICYCLIC SYSTEM RELATED TO TAXANES, Tetrahedron letters, 39(20), 1998, pp. 3133-3136
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
20
Year of publication
1998
Pages
3133 - 3136
Database
ISI
SICI code
0040-4039(1998)39:20<3133:M8R-AT>2.0.ZU;2-I
Abstract
Addition of Me2CuLi, with in situ trapping by TMSCl, to Hagemann's est er derivative 13, furnished silyl enol ether 14. Mukaiyama-type cycliz ation of the latter compound gave the tricyclic derivative 15. structu rally related to the taxane core. (C) 1998 Elsevier Science Ltd. All r ights reserved.