REMARKABLE EFFECT OF LITHIUM BROMIDE IN THE ENANTIOSELECTIVE PROTONATION WITH ALPHA-SULFINYL ALCOHOLS

Authors
ASENSIO G ALEMAN PA DOMINGO LR MEDIOSIMON M
Citation
G. Asensio et al., REMARKABLE EFFECT OF LITHIUM BROMIDE IN THE ENANTIOSELECTIVE PROTONATION WITH ALPHA-SULFINYL ALCOHOLS, Tetrahedron letters, 39(20), 1998, pp. 3277-3280
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
20
Year of publication
1998
Pages
3277 - 3280
Database
ISI
SICI code
0040-4039(1998)39:20<3277:REOLBI>2.0.ZU;2-L
Abstract
The favourable effect of lithium bromide enhancing the facial enantios electivity in the protonation of methyl tetralone enolate with alpha-s ulfinyl alcohols is described. Theoretical calculations allow to propo se a model to explain the stereochemical course of the protonation rea ction. (C) 1998 Elsevier Science Ltd. All rights reserved.