ASMARINES A-C - 3 NOVEL CYTOTOXIC METABOLITES FROM THE MARINE SPONGE RASPAILIA SP

Authors
YOSIEF T RUDI A STEIN Z GOLDBERG I GRAVALOS GMD SCHLEYER M KASHMAN Y
Citation
T. Yosief et al., ASMARINES A-C - 3 NOVEL CYTOTOXIC METABOLITES FROM THE MARINE SPONGE RASPAILIA SP, Tetrahedron letters, 39(20), 1998, pp. 3323-3326
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
20
Year of publication
1998
Pages
3323 - 3326
Database
ISI
SICI code
0040-4039(1998)39:20<3323:AA-3NC>2.0.ZU;2-5
Abstract
Three novel nitrogen-containing metabolites, asmarines A-C (1 - 3) tog ether with two known diterpenes, zaatirin and chelodane were isolated from the Red Sea sponge Raspailia sp, collected in the Dahlak archipel ago, Eritrea. The structure of the three new compounds and the known z aatirin and chelodane were established by spectroscopic analysis inclu ding X-ray diffraction analysis for asmarine A. Asmarines A-C are cyto toxic to a few human cancer cells, (C) 1998 Elsevier Science Ltd. All rights reserved.