Mechanical or artificial ventilation is the most important life-saving
therapeutic instrument in modern intensive care medicine. The ventila
tor takes on the convective transport of the respiratory gas, i.e. del
ivery of oxygen and removal of carbon dioxide. The technical gas deliv
ery system (ventilator, respiratory tubing system, gas humidifier) and
the respiratory system (lungs and thorax) of the patient form a conne
cted pneumatic system of high complexity. The respiratory system produ
ces a mechanical impedance to ventilator output. Impedance is composed
of an elastic, a non-elastic, i.e. resistive, and an inertive part. T
he corresponding indices describing respiratory mechanics are complian
ce, flow resistance and inertance. Based on the equation of motion of
the respiratory system, several methods of analysing respiratory mecha
nics during mechanical ventilation are described. Quantitative analysi
s of respiratory system mechanics (a)is a prerequisite for the underst
anding of the complex patient-ventilator interaction, (b) provides imp
ortant clinical information on pulmonary function and the course of di
sease, and (c) allows the physician at the bedside to adjust the venti
latory settings to the needs of the individual patient.