BRAIN SPECT IMAGING USING 3 DIFFERENT TRACERS IN SUBACUTE CEREBRAL INFARCTION

Two patients with subacute cerebral infarction underwent benzodiazepin e receptor imaging using I-123-iomazenil and cerebral perfusion imagin g with Tc-99m HMPAO and Tc-99m ECD. Iomazenil early images resembled H MPAO images, which demonstrated increased uptake in a part of the infa rcted site, Iomazenil delayed images and ECD images showed reduced acc umulation in the same area. Crossed cerebellar diaschisis was observed in HMPAO, ECD, and iomazenil early images, but it was not remarkable in iomazenil delayed images. These cases suggest that sequential iomaz enil images visualized increased uptake with relatively impaired viabi lity in the infarcted site and hypoperfusion with preserved viability in the contralateral cerebellar hemisphere, which could not be recogni zed without using both HMPAO and ECD in the subacute phase of cerebral infarction.