GASTROINTESTINAL REGULATORY PEPTIDES TARG ET OF IONIZING-RADIATION - FUNCTIONAL ALTERATIONS

The symptoms associated with exposure to ionizing radiation are nausea , vomiting, diarrhoea. The response of the gut is complex involving mo difications of motility and fluid and Electrolyte transport. Gastroint estinal regulatory peptides have an important role in these functions. This study showed that radiation-induced tissue variations of neurope ptides have some repercussions on intestinal biological activity of th ese peptides soon after irradiation. In addition such modifications ar e also seen a few years after irradiation.