F. Teyssier et al., ADDITIVE EFFECT OF MILD HYPERTHERMIA AND IONIZING-RADIATION IN 2 COLON-TUMOR CELL-LINES, Journal de chimie physique et de physico-chimie biologique, 95(4), 1998, pp. 875-877
We have examined the effect of mild hyperthermia (42 degrees C for 1 h
our) on the radiosensitivity of Colo205 and Colo320DM, two human colon
tumor cell lines which express respectively wild-type and mutated p53
protein. In both cell lines, the benefits of the association hyperthe
rmia-irradiation result from an additive effect of both treatments and
not from an hyperthermic sensitization of radiation.