D. Trauner et al., NEW VENTURES IN THE CONSTRUCTION OF COMPLEX HETEROCYCLES - SYNTHESIS OF MORPHINE AND HASUBANAN ALKALOIDS, Synthesis, 1998, pp. 653-664
Synthetic approaches to morphine and hasubanan alkaloids involving nov
el reactions for the formation of their dihydrobenzofuran, piperidine
and pyrrolidine ring, respectively, are described. The importance of c
onformational constraints for the success of these reactions is demons
trated. The syntheses of new dioxepanes, diazepanes, dithiocanes, tria
zenes and dioxonanes are also reported.