The upper airway is a complex structure that can be affected in a numb
er of ways in patients with rheumatic diseases. Respiration is maintai
ned through the upper airway; therefore, any obstruction to this passa
ge is a potentially life-threatening event. Although airway obstructio
n can be effectively managed, suspicion for the diagnosis is necessary
prior to initiating the appropriate care. This article reviews the me
chanisms of airway obstruction, its symptoms and evaluation, and the s
pecific upper airway manifestations that can occur in patients with rh
eumatic diseases.