Purpose. Using staining pigments with which we had gained experience i
n dermatography (medical tattooing) treatments of leucoma corneae, a n
ew approach was developed to create an artificial iris-like staining a
t the mid-stromal level of the cornea to treat photophobia in a patien
t with posttraumatic aniridia. Methods. After a central 4-mm half-dept
h trephination, a lamellar dissection of the corneal stroma toward the
limbus was performed. A combination of colored pigments was introduce
d into this midstromal space, until a light blue artificial iris (to m
atch the contralateral eye) with adequate blocking of light was create
d. Results. A stable artificial iris was created in the mid-stromal le
vel of the cornea. Conclusion. Dermatography pigments are stable in th
e corneal stroma and are useful to treat photophobia in aniridia follo
wing trauma.