COCHINOLIDE, A NEW GAMMA-ALKYLIDENE BICYCLIC BUTENOLIDE WITH ANTIVIRAL ACTIVITY, AND ITS BETA-GLUCOPYRANOSIDE FROM HOMALIUM-COCHINCHINENSIS

Authors
ISHIKAWA T NISHIGAYA K UCHIKOSHI H CHEN IS
Citation
T. Ishikawa et al., COCHINOLIDE, A NEW GAMMA-ALKYLIDENE BICYCLIC BUTENOLIDE WITH ANTIVIRAL ACTIVITY, AND ITS BETA-GLUCOPYRANOSIDE FROM HOMALIUM-COCHINCHINENSIS, Journal of natural products, 61(4), 1998, pp. 534-537
Citations number
7
Categorie Soggetti
Chemistry Medicinal","Plant Sciences","Pharmacology & Pharmacy",Chemistry
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
61
Issue
4
Year of publication
1998
Pages
534 - 537
Database
ISI
SICI code
0163-3864(1998)61:4<534:CANGBB>2.0.ZU;2-8
Abstract
A new gamma-alkylidene bicyclic butenolide designated as cochinolide ( 1) and its beta-glucopypanoside (3) were isolated from the root bark o f Homalium cochinchinensis (Flacoutiaceae). Their structures, except a bsolute stereochemistries, were determined by spectroscopic means. Coc hinolide (1) showed moderate antiviral activities against HSV-1 and -2 .