DETECTION OF A DECARBOXYLATED DIMER OF AMINOETHYLCYSTEINE KETIMINE INBOVINE CEREBELLUM

Aminoethylcysteine ketimine is a sulfur-containing cyclic compound pro duced by the enzymatic alpha-deamination of the parent aminoethylcyste ine that has been detected in bovine brain and cerebellum. Aminoethylc ysteine ketimine is known to dimerize spontaneously and easily lose on e carboxyl group. This decarboxylated compound, simply named the dimer , has been recently detected in normal human urine. In this article we provide evidence on the occurrence of the dimer in the bovine cerebel lum. (C) 1998 Elsevier Science Ltd. All rights reserved.