POROUS ALUMINA ORBITAL IMPLANT FOR RABBIT MODEL - PRELIMINARY-RESULTS

Purpose Evaluation of clinical tolerance and scanning electron microsc opy study of the bio-colonisation of a porous ceramical alumina implan t after evisceration of the rabbit. Preliminary results. Methods Sixte en white New Zealand rabbits were eviscerated. A porous hydroxyde alum ina ball was implanted in the opened sclera and explanted 15, 30, and 90 days after implantation. Clinical tolerance was assessed and implan t tissular ingrowth was analyzed by scanning electron microscopy. Resu lts One infection was observed and there was no conjunctival breakdown . Fibrovascular ingrowth occurred as soon as 15 days after implantatio n, and was full at one month. Conclusion Porous alumina implant orbita l tissue tolerance and fast fibrovascular ingrowth in the rabbit socke t suggest promising result in the human anophthalmic socket.