HEMOCHROMATOSIS OF THE FOOT AND ANKLE - REPORT OF 3 CASES AND REVIEW OF THE LITERATURE

Genetic hemochromatosis is a disorder of iron metabolism that results in deposition of massive amounts of iron in the tissues. Arthropathy i s one of numerous clinical manifestations associated with this disease . Characteristic radiographic features have been reported in the hand and wrist, and the hip; however, there is no mention in the literature of joint manifestations in the foot and ankle, In this report, the au thors present three patients with hemochromatosis arthropathy of the f oot and ankle. Two patients presented primarily with foot pain and wer e treated initially with orthoses, One of these patients went on to ha ve to midfoot arthrodesis performed. The third patient presented with ankle joint symptoms, and was treated successfully with an ankle foot orthosis. The arthritis of hemochromatosis has classic radiographic fi ndings. However, the arthritis of hemochromatosis may be difficult to differentiate from several other joint diseases. Characteristic featur es of this disease in the foot and ankle are discussed.