UNEXPECTED LATE GRAFT FAILURE 9 MONTHS AFTER HLA-IDENTICAL BONE-MARROW TRANSPLANT (BMT) FOR CHRONIC MYELOID-LEUKEMIA (CML) - TREATMENT WITHA 2ND BMT

Authors
GILFERNANDEZ JJ ARRANZ R CAMARA R ALEGRE A FIGUERA A FERNANDEZRANADA JM
Citation
Jj. Gilfernandez et al., UNEXPECTED LATE GRAFT FAILURE 9 MONTHS AFTER HLA-IDENTICAL BONE-MARROW TRANSPLANT (BMT) FOR CHRONIC MYELOID-LEUKEMIA (CML) - TREATMENT WITHA 2ND BMT, Haematologica, 83(3), 1998, pp. 285-287
Citations number
10
Categorie Soggetti
Hematology
Journal title
Haematologica → ACNP
ISSN journal
03906078
Volume
83
Issue
3
Year of publication
1998
Pages
285 - 287
Database
ISI
SICI code
0390-6078(1998)83:3<285:ULGF9M>2.0.ZU;2-J
Abstract
We describe a patient with CML in 1(st) chronic phase (CP) who experie nced a graft failure 9 months after an HLA genotypically identical sib ling BMT. Drug toxicity, viral infections, chronic graft-versus-host-d isease (GVHD) or leukemic relapse were excluded. Chimerism study showe d 85% of donor marrow cells. She underwent a second BMT, reengrafted b ut died of grade IV acute GVHD.