Background: An experimental study in a porcine model was undertaken to
evaluate the currently available techniques of laparoscopic vagotomy.
Methods: Four groups of pigs were studied. Under general anesthesia,
the animals were submitted to either bilateral vagotomy, bilateral hig
hly selective vagotomy, posterior truncal vagotomy with anterior highl
y selective vagotomy, or Taylor's procedure. Gastric acid secretion an
d intestinal motility were evaluated before and after the surgical pro
cedure. The feasibility of the four different techniques was assessed
by means of a personal difficulty score. Results: All four procedures
produced significant acid secretory reduction. Multivariate analysis s
howed that the factor most affecting the outcome was the difficulty sc
ore. Conclusions: Taylor's procedure was the easiest and safest techni
que. It also produced the best functional results for secretion and mo
tility.