OKADAIC ACID PRODUCTION FROM THE MARINE DINOFLAGELLATE PROROCENTRUM-BELIZEANUM FAUST ISOLATED FROM THE BELIZEAN CORAL-REEF ECOSYSTEM

Authors
MORTON SL MOELLER PDR YOUNG KA LANOUE B
Citation
Sl. Morton et al., OKADAIC ACID PRODUCTION FROM THE MARINE DINOFLAGELLATE PROROCENTRUM-BELIZEANUM FAUST ISOLATED FROM THE BELIZEAN CORAL-REEF ECOSYSTEM, Toxicon, 36(1), 1998, pp. 201-206
Citations number
14
Categorie Soggetti
Toxicology,"Pharmacology & Pharmacy
Journal title
Toxicon → ACNP
ISSN journal
00410101
Volume
36
Issue
1
Year of publication
1998
Pages
201 - 206
Database
ISI
SICI code
0041-0101(1998)36:1<201:OAPFTM>2.0.ZU;2-G
Abstract
A species of epiphytic Prorocentrum (Dinophyta, Prorocentrales), colle cted from the macroalga Dictyota dichotoma, was brought into culture. Based on morphological characteristics, this isolate was identified as Prorocentrum belizeanum. Analysis of the culture extract using high-p erformance liquid chromatography and liquid chromatography-mass spectr ometry indicated the production of okadaic acid, a toxic polyether lin ked with the human diseases, diarrhetic shellfish poisoning and ciguat era fish poisoning. (C) 1998 Elsevier Science Ltd. All rights reserved .