PD CU-CATALYZED COUPLINGS OF BETA-AMINO ESTERS WITH ARYL BROMIDES - SYNTHESIS OF CHIRAL 1,2,3,4-TETRAHYDRO-4-OXO-2-ALKYL-1-QUINOLINES/

Authors
MA DW JIANG JQ
Citation
Dw. Ma et Jq. Jiang, PD CU-CATALYZED COUPLINGS OF BETA-AMINO ESTERS WITH ARYL BROMIDES - SYNTHESIS OF CHIRAL 1,2,3,4-TETRAHYDRO-4-OXO-2-ALKYL-1-QUINOLINES/, Tetrahedron : asymmetry, 9(7), 1998, pp. 1137-1142
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
7
Year of publication
1998
Pages
1137 - 1142
Database
ISI
SICI code
0957-4166(1998)9:7<1137:PCCOBE>2.0.ZU;2-E
Abstract
A new protocol to prepare chiral 1,2,3,4-tetrahydro-4-oxo-2-alkyl-1-qu inolines has been developed. The key steps are Pd/Cu-catalyzed couplin gs of chiral beta-amino esters and aryl bromides, and intramolecular a cylation. (C) 1998 Elsevier Science Ltd. All rights reserved.